Friday, May 30, 2014

Targeted Plexxikon Drug Helps Ease Joint Pain

Image: Daiichi Sankyo Logo
Source: Google Serach
Plexxikon, a unit of Daiichi Sankyo, has developed experimental cancer drug that can also help to ease pain and swelling in various joint disease that are caused by genetic mutation.
This finding and revelation of the genetic underpinnings of cancer has much more lead to mutations related problem treatment.

Recurrent pigmented villonodular synovitis, or PVNS is a disease that is caused by a glitch causes cells to overproduce stimulating factor 1. This cell destroys the soft normal tissue of joints. Thus the new drug Plexxikon's drug, PLX3397 acts against PVNS by blocking its abnormality.

This drug was tested by Memorial Sloan-Kettering Cancer Center in New York on 600 600 people in the United States.

This drug is proving good because joint pain it is somewhat same but  does not spread to other parts of the body.

The result declared by evaluating 11 out 14 patients result. The results were good and they response to the drug, along with that tumor shrank at least by half, and 3 patients had stable disease. On average, 61% tumors shrank.

Dr William Tap of Memorial Sloan-Kettering, who led the study said –“These results are a shining example of how patients can experience a meaningful clinical benefit when we are able to match the right treatment with the right target.”

Dr Clifford Hudis, president of American Society of Clinical Oncology, also aparies this study and said that-“at future treatments that will become possible as a result of efforts to better match patients”

Thus a final study will be presented at the ASCO meeting in Chicago starting on May 30 and will end on June 3.

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